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Systematic Review

This guide aims to provide tools and resources that can be used for conducting a systematic review in medical and health sciences.

Standards and Methods

Refer to the following standards and guidelines to ensure your systematic reviews are trustworthy, accurately documented, and in high quality.

AHRQ Methods Guide for Effectiveness and Comparative Effectiveness Reviews 

Comparative effectiveness reviews are systematic reviews of existing research on the effectiveness, comparative effectiveness, and harms of different health care interventions. This guide presents issues key to the development of comparative effectiveness reviews and describes recommended approaches for addressing difficult, frequently encountered methodological issues.


Methodological Expectations of Campbell Collaboration Intervention Reviews (MECCIR)

Standards for the conduct and reporting of Campbell systematic reviews of intervention effects.

Campbell systematic reviews: Policies and guidelines (Version 1.7)

This document articulates the policies that pertain to the nature and production of Campbell systematic reviews as approved by the Campbell Collaboration Technical Advisory Group. It is designed to inform review teams and potential review teams about the requirements for Campbell systematic reviews, guidelines for producing them, and selected sources of further information about systematic reviews that is consistent with those requirements and guidelines.



Cochrane Handbook for Systematic Reviews of Interventions (Version 6.3, 2022)

EPPI – Centre (The Evidence for Policy and Practice Information and Co-ordinating Centre)

Provides resources on systematic review & evidence synthesis methodology

IOM (Institute of Medicine) - Finding what works in health care: standards for systematic reviews

The IOM's standards address the entire systematic review process, from locating, screening, and selecting studies for the review, to synthesizing the findings (including meta-analysis) and assessing the overall quality of the body of evidence, to producing the final review report.

JBI (Joanna Briggs Institute) Manual for Evidence Synthesis

MECIR (Methodological Expectations of Cochrane Intervention Reviews) (version Feb 2022)

Standards for the conduct and reporting of new Cochrane Intervention Reviews, reporting of protocols and the planning, conduct and reporting of updates.

PRISMA 2020 Checklist (updated in March 2021)

The checklist contains 27 items addressing the introduction, methods, results and discussion sections of a systematic review report. PRISMA Flow Diagram depicts the flow of information through the different phases of a systematic review. It maps out the number of records identified, included and excluded, and the reasons for exclusions. Different templates are available depending on the type of review (new or updated) and sources used to identify studies.